A randomized phase III clinical trial to evaluate the feasibility and clinical relevance of liquid biopsy in patients with suspicious metastatic or locally advanced lung cancer.
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Mis à jour le 12/07/2024
Cancers thoraciques respiratoires (cbnpc/cbpc)

Informations générales
  • Titre abrégé

    Libelule

  • Phase de l'essai
    • Phase III

Promoteur
  • Type de promoteur

    Académique / Institutionnel

  • Nom du promoteur

    CENTRE LEON BERARD


Critères d'inclusion
  • I1. Age e" 18 years, I2. Patients with clinico-radiological suspicious presentation of lung cancer locally advanced not amendable to a locoregional treatment or stage IV, I3. No prior chemotherapy for locally advanced or metastatic NSCLC, I4. Eastern Cooperative Oncology Group (ECOG) Performance Status 0-2, I5. Life expectancy > 12 weeks, I6. No contraindication to systemic lung cancer treatment, I7. No planned or previous inclusion in another 1st line therapy study, I8. Covered by a medical insurance, I9. Signed informed consent prior to any study-specific procedure, I10. No prior biopsy or cytology for this lung cancer diagnosis

Critères d'exclusion
  • Pregnant or breastfeeding woman, E2. Patient concurrently using other approved or investigational antineoplastic agents, E3. Major concurrent disease affecting cardiovascular system, liver, kidneys, hematopoietic system or else considered as clinically important by the investigator and that could be incompatible with patient s participation in this trial or would likely interfere with study procedures or results, E4. Prior history of malignancies other than study disease (except for basal cell or squamous cell carcinoma of the skin or carcinoma in situ of the cervix) unless the patient has been free of the disease for at least 3 years, E5. Patient requiring tutorship or curatorship.

Centre investigateur 1
  • Nom du centre

    HCL - Hôpital Louis Pradel
    Lyon

  • Contact Investigateur

  • Nom

    Michael DURUISSEAUX

  • Contact ARC/TER/IRC

  • Nom

    Raphaele GUELMINGER